Neuroma vs Neurofibroma

Neuroma vs Neurofibroma (What is Difference)

In this article, we are going to know about What is the difference between a neurofibroma and a neuroma and will try to learn about it. A neuroma is a disorganized growth of nerve cells at the site of a nerve injury. A neuroma occurs after a nerve is partially or completely interrupted by injury, either due to a cut, crush, or excessive stretching.

Our feet take a lot of punishment, whether it’s long walks, extreme workouts, or even wearing high heels. We often don’t realize how many hours we’re on our feet, and that can be a problem. Like many of you.


A neuroma is a general term applied to any of several different things (neoplastic or non-neoplastic) that cause a nerve or nerve bundle to swell. Usually another word is attached to give a more specific meaning.

Neuroma Symptoms:

  • Shooting Pain
  • Burning
  • Numbness

Neoplastic neuromas are tumors of any part of a nerve (including the surrounding myelin); sometimes the term is used more broadly to refer to any tumor of neural tissue. An example of a neoplastic neuroma is the acoustic neuroma, a benign tumor that surrounds the eighth cranial nerve (you can also call this tumor a schwannoma, since it is a neoplasm derived from the Schwann cells that surround the nerve, not the nerve itself) .

The main non-neoplastic neuromas are the traumatic neuroma (a non-neoplastic reaction of a nerve to some type of damage) and Morton’s neuroma (which is not even a neuroma, but a collection of fibrous tissue around a nerve, usually in the foot ).



More about Neuroma:

What are Neuromas and how are they treated? Our feet take a lot of punishment, whether it’s long walks, extreme workouts, or even wearing high heels.  We often don’t realize how many hours we’re on our feet, and that can be a problem.  Like many of you.  I’m on my feet much of the time.  And recently I felt a pain in my foot.  And I thought, well, it’ll go away, but it didn’t.  So I knew it was time to see the doctor. It was a shooting pain between my toes.  I was diagnosed with a fairly common problem, and Aroma and Aromas are pinching of a nerve where the nerve gets pinched between to the bones there in the foot.

It can occur in different areas of the foot.  But typically in between the third and fourth toes and the nerve gets irritated in there, it gets enlarged because of the constant irritation, whether it be from shoes, whether it be from an increase in activity to foster an increase in activity or someone’s foot hype.

Just being in that situation where it gets you irritated nerve can become pinched in a one-time situation, like wearing a pair of shoes that are too tight or from a trauma to the foot, or it can happen slowly over time, from repeated use or stress, which can aggravate an inflamed the nerve. Its more common in women just because women shoes tend to be a little bit snugger up across the front part of the foot.  But anyone can get it.  People tend to notice neuromas more in the fall when they start wearing closed-toed shoes.

 The symptoms are usually shooting pain with burning or numbness. And as the nerve gets more irritated, it swells more causing even more pain.  So how do you treat a neuroma first modify the shoes you wear making sure there’s plenty of room for the toes to spread out?

If more attention is needed, sometimes we’ll use a steroid injection to kind of calm down, just inflammation in general.  In that area, we first tried these steroid injections to see if we could reduce the inflammation in my foot.  But that didn’t work.  So oh, now we’re onto something else.  We’re kind of the point of most of the conservative things that haven’t worked.  So at that point, we go to injections like an alcohol injection, which can truly destroy the nerve without having to do surgery.

A numbing spray goes on first, and then the alcohol injection goes in the top of the foot directly into the nerve.  It’s a small pinch and a little burn are we done?   Usually, a series of three to seven injections will destroy the nerve and stop the pain.  If that doesn’t work, the last option is surgery to remove the nerve completely.  And if you don’t treat the neuroma, doctors say it typically won’t cause any long-term damage to the foot.  But there could be unintended consequences.  You don’t have it treated, it can continue to cause pain, which can then cause you to favor it, or walk differently.  And a lot of times those things happen from compensating, whether it be you walk in and walking with a limp, and all of a sudden your hips hurting your knees hurting, or something like that.



Neurofibromas are benign neoplasms arising from the myelin sheath of peripheral nerves (just a reminder: the myelin surrounding peripheral nerves is supplied by Schwann cells; the myelin surrounding central nerves is supplied by oligodendrocytes). They often occur in the setting of neurofibromatosis, an inherited condition characterized by multiple cutaneous neurofibromas, pigmented skin lesions, skeletal abnormalities, microcephaly, epilepsy, and many other findings. In the photo above, the patient has multiple neurofibromas scattered throughout the body.

what is Neurofibroma

Neurofibromas are like schwannomas in that they are derived from Schwann cells. However, a schwannoma has mainly Schwann cells, while a neurofibroma has many other cell types, such as fibroblasts, endothelial cells, and mast cells.


Dr. Holly firfer CNN, Atlanta.

Kristine Krafts, MD,

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